Mar 29, 2024  
OHIO University Graduate Catalog 2019-20 
    
OHIO University Graduate Catalog 2019-20 [Archived Catalog]

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BIOS 5100 - Biological Pharmacology


An over-arching synthesis of concepts already learned in cell biology, genetics, physiology and chemistry are applied to the biological principles of drug action. Designed as a capstone experience for students in the sciences, especially the biological sciences. Covers the pathophysiology and therapeutic uses of drugs, for certain human diseases (e.g., heart failure, diabetes, Parkinson’s disease, and infectious diseases). A select group of the most commonly prescribed drugs are discussed in terms of their cellular mechanisms of action and how drug actions alter disease states. After successfully completing the learning activities students are better prepared for biomedical careers after graduation. Toxicology and medicinal chemistry of various drug classes are not discussed.

Requisites:
Credit Hours: 3
Repeat/Retake Information: May not be retaken.
Lecture/Lab Hours: 3.0 lecture
Grades: Eligible Grades: A-F,WP,WF,WN,FN,AU,I
Learning Outcomes:
  • Students will be able to classify drug classes by their cellular and/or physiological mechanisms of action, and when appropriate, make a list of drugs as either agonists or antagonists
  • Students will be able to compare various drugs as to their cellular mechanism of action, adverse effects, and drug interactions and make a judgement as to which drug is better suited for a given therapeutic application
  • Students will be able to understand dose-response curves and predict changes as a result of various experimental and drug induced outcomes
  • Students will be able to describe the major classes of receptors for each of the primary neurotransmitters and their associated effector systems
  • Students will be able to describe homeostasis, fight-or-flight, and rest-and-repair with regard to the autonomic nervous system
  • Students will be able to construct and analyze signal transduction pathways that are influenced by drugs
  • Students will be able to define bacterial resistance and illustrate the mechanisms involved in acquiring bacterial resistance
  • Students will be able to research original resources to create a written term report on critical drug issues for the 21st century
  • Students will be able to analyze and critique statements and arguments made about pharmacologic agents, using scientific evidence.
  • Students will be able to prepare and give an oral presentation on an original research project



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